- Authors
- Andrew T. Gloster Technische Universität Dresden, Institute of Clinical Psychology and Psychotherapy, Germany
- Rainer Sonntag
- Jürgen HoyerTechnische Universität Dresden, Institute of Clinical Psychology and Psychotherapy, Germany
- Andrea H. Meyer
- Simone Heinze
- Andreas Ströhle
- Georg Eifert
- Hans-Ulrich Wittchen
- title
- Treating Treatment-Resistant Patients with Panic Disorder and Agoraphobia Using Psychotherapy
- subtitle0
- A Randomized Controlled Switching Trial
- Please use the following URL when quoting:
- https://nbn-resolving.org/urn:nbn:de:bsz:14-qucosa2-716402
- original0000000000000
- Psychotherapy and Psychosomatics Erscheinungsort: Basel
Verlag: Karger
Erscheinungsjahr: 2015
Jahrgang: 84
Heft: 2
Seiten: 100-109
E-ISSN: 1423-0348 - publication_date
- 2015
- Abstract (EN)
- Background: Nonresponsiveness to therapy is generally acknowledged, but only a few studies have tested switching to psychotherapy. This study is one of the first to examine the malleability of treatment-resistant patients using acceptance and commitment therapy (ACT). Methods: This was a randomized controlled trial that included 43 patients diagnosed with primary panic disorder and/or agoraphobia (PD/A) with prior unsuccessful state-of-the-art treatment (mean number of previous sessions = 42.2). Patients were treated with an ACT manual administered by novice therapists and followed up for 6 months. They were randomized to immediate treatment (n = 33) or a 4-week waiting list (n = 10) with delayed treatment (n = 8). Treatment consisted of eight sessions, implemented twice weekly over 4 weeks. Primary outcomes were measured with the Panic and Agoraphobia Scale (PAS), the Clinical Global Impression (CGI), and the Mobility Inventory (MI). Results: At post-treatment, patients who received ACT reported significantly more improvements on the PAS and CGI (d = 0.72 and 0.89, respectively) than those who were on the waiting list, while improvement on the MI (d = 0.50) was nearly significant. Secondary outcomes were consistent with ACT theory. Follow-up assessments indicated a stable and continued improvement after treatment. The dropout rate was low (9%). Conclusions: Despite a clinically challenging sample and brief treatment administered by novice therapists, patients who received ACT reported significantly greater changes in functioning and symptomatology than those on the waiting list, with medium-to-large effect sizes that were maintained for at least 6 months. These proof-ofprinciple data suggest that ACT is a viable treatment option for treatment-resistant PD/A patients. Further work on switching to psychotherapy for nonresponders is clearly needed.
- otherVersion00000
- Link zum Artikel der zuerst in der Zeitschrift 'Psychotherapy and Psychosomatics' erschienen ist
DOI: 10.1159/000370162 - Keywords (DE)
- Non-Responder, behandlungsresistente Patienten, Therapiewechsel, Akzeptanz- und Bindungstherapie, Panikstörung, Agoraphobie
- Keywords (EN)
- Nonresponders, Treatment-resistant patients, Therapy switching, Acceptance and commitment therapy, Panic disorder, Agoraphobia
- Classification (DDC)
- 610
- Publishing house
- Karger, Basel
- Project sponsoring
- Ministerium für Bildung und Forschung
BMBF-Psychotherapie-Forschung
ID: 01GV0615 - version
- publizierte Version / Verlagsversion
- URN Qucosa
- urn:nbn:de:bsz:14-qucosa2-716402
- Qucosa date of publication
- 05.08.2020
- Document type
- article
- Document language
- English
- licence