- AutorIn
- Angela Emmrich
- Katja Beesdo-Baum
- Andrew T. Gloster
- Susanne Knappe
- Michael Höfler
- Volker Arolt
- Jürgen Deckert
- Alexander L. Gerlach
- Alfons Hamm
- Tilo Kircher
- Thomas Lang
- Jan Richter
- Andreas Ströhle
- Peter Zwanzger
- Hans-Ulrich Wittchen
- Titel
- Depression Does Not Affect the Treatment Outcome of CBT for Panic and Agoraphobia: Results from a Multicenter Randomized Trial
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:14-qucosa-133613
- Quellenangabe
- Psychother Psychosomatics 2012;81:161–172, ISSN: 0033-3190
- Erstveröffentlichung
- 2012
- Abstract (DE)
- Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
- Abstract (EN)
- Background: Controversy surrounds the questions whether co-occurring depression has negative effects on cognitivebehavioral therapy (CBT) outcomes in patients with panic disorder (PD) and agoraphobia (AG) and whether treatment for PD and AG (PD/AG) also reduces depressive symptomatology. Methods: Post-hoc analyses of randomized clinical trial data of 369 outpatients with primary PD/AG (DSM-IV-TR criteria) treated with a 12-session manualized CBT (n = 301) and a waitlist control group (n = 68). Patients with comorbid depression (DSM-IV-TR major depression, dysthymia, or both: 43.2% CBT, 42.7% controls) were compared to patients without depression regarding anxiety and depression outcomes (Clinical Global Impression Scale [CGI], Hamilton Anxiety Rating Scale [HAM-A], number of panic attacks, Mobility Inventory [MI], Panic and Agoraphobia Scale, Beck Depression Inventory) at post-treatment and follow-up (categorical). Further, the role of severity of depressive symptoms on anxiety/depression outcome measures was examined (dimensional). Results: Comorbid depression did not have a significant overall effect on anxiety outcomes at post-treatment and follow-up, except for slightly diminished post-treatment effect sizes for clinician-rated CGI (p = 0.03) and HAM-A (p = 0.008) when adjusting for baseline anxiety severity. In the dimensional model, higher baseline depression scores were associated with lower effect sizes at post-treatment (except for MI), but not at follow-up (except for HAM-A). Depressive symptoms improved irrespective of the presence of depression. Conclusions: Exposure-based CBT for primary PD/AG effectively reduces anxiety and depressive symptoms, irrespective of comorbid depression or depressive symptomatology.
- Andere Ausgabe
- DOI: 10.1159/000335246
- Volltext des Artikels, der zuerst in der Zeitschrift "Psychother Psychosomatics" des Karger-Verlages erschienen ist.
Link: http://dx.doi.org/10.1159/000335246 - Freie Schlagwörter (DE)
- Panikstörung, Agoraphobie, Angststörung, Depression, Komorbidität, Verhaltenstherapie, randomisierte kontrollierte Studie
- Freie Schlagwörter (EN)
- Panic disorder, Agoraphobia, Depression, Comorbidity, Cognitive-behavioral therapy, Exposure, Randomized controlled trial
- Klassifikation (DDC)
- 610, 150
- Klassifikation (RVK)
- XA 10000, CL 1000
- Verlag
- Karger, Basel
- URN Qucosa
- urn:nbn:de:bsz:14-qucosa-133613
- Veröffentlichungsdatum Qucosa
- 13.02.2014
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis