- AutorIn
- Andrew T. Gloster
- Hans-Ulrich Wittchen
- Franziska Einsle
- Michael Höfler
- Thomas Lang
- Sylvia Helbig-Lang
- Thomas Fydrich
- Lydia Fehm
- Alfons O. Hamm
- Jan Richter
- Georg W. Alpers
- Alexander L. Gerlach
- Andreas Ströhle
- Tilo Kircher
- Jürgen Deckert
- Peter Zwanzger
- Volker Arolt
- Titel
- Mechanism of action in CBT (MAC): methods of a multi-center randomized controlled trial in 369 patients with panic disorder and agoraphobia
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:14-qucosa-106614
- Quellenangabe
- European Archives of Psychiatry and Clinical Neuroscience, Bd. 259 (2009), Nr. 2 Supplement, S. 155-166, ISSN: 0940-1334 , EISSN: 1433-8491
- Erstveröffentlichung
- 2009
- Abstract (EN)
- Cognitive behavioral therapy (CBT) is efficacious for panic disorder with agoraphobia (PD/A). Nevertheless, the active ingredients of treatment and the mechanisms through which CBT achieves its effects remain largely unknown. The mechanisms of action in CBT (MAC) study was established to investigate these questions in 369 patients diagnosed with PD/A. The MAC study utilized a multi-center, randomized controlled design, with two active treatment conditions in which the administration of exposure was varied, and a wait-list control group. The special feature of MAC is the way in which imbedded experimental, psychophysiological, and neurobiological paradigms were included to elucidate therapeutic and psychopathological processes. This paper describes the aims and goals of the MAC study and the methods utilized to achieve them. All aspects of the research design (e.g., assessments, treatment, experimental procedures) were implemented so as to facilitate the detection of active therapeutic components, and the mediators and moderators of therapeutic change. To this end, clinical, behavioral, physiological, experimental, and genetic data were collected and will be integrated.
- Andere Ausgabe
- DOI: 10.1007/s00406-009-0065-6
- Link zur publizierten Version des Artikels, der in der Zeitschrift "European Archives of Psychiatry and Clinical Neuroscience" des Springer-Verlags erschienen ist.
Link: http://dx.doi.org/10.1007/s00406-009-0065-6 - Freie Schlagwörter (DE)
- Panikstörung, Agoraphobie, kognitiv-behaviorale Therapie, Konfrontationstherapie, Mechanismen, Methoden
- Freie Schlagwörter (EN)
- Panic disorder, Agoraphobia, CBT, Exposure therapy, Mechanisms, Methods
- Klassifikation (DDC)
- 150
- Klassifikation (RVK)
- CU 3100, CU 8500
- Publizierende Institution
- Technische Universität Dresden, Dresden
- URN Qucosa
- urn:nbn:de:bsz:14-qucosa-106614
- Veröffentlichungsdatum Qucosa
- 22.02.2013
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis