- Titel
- Directed evolution of an HIV-1 LTR specific recombinase for anti-retroviral therapy- a proof of concept study
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:swb:14-1169028775210-26417
- Datum der Einreichung
- 14.06.2006
- Datum der Verteidigung
- 26.09.2006
- Abstract (EN)
- The prospect of the work presented in this thesis has been to engineer Cre recombinase to recognize and recombine a sequence from an HIV-1 Long Terminal Repeat (LTR), characterize the recombination proficiency of the evolved recombinase in mammalian cells and explore the potential of the recombinase for a novel antiretroviral strategy.
- Freie Schlagwörter (DE)
- Cre Rekombinase, HIV, DNA Evolution, antiretrovirale Therapie
- Freie Schlagwörter (EN)
- Cre recombinase, HIV, directed evolution, antiretroviral strategy
- Klassifikation (DDC)
- 570
- Klassifikation (RVK)
- XD 8000
- Normschlagwörter (GND)
- HIV, DNS, Evolution, Antiretrovirale Substanz
- GutachterIn
- Dr. Frank Buchholz
- Prof. Dr. Francis Stewart
- Prof. Dr. Joachim Hauber
- BetreuerIn
- Dr. Frank Buchholz
- Verlag
- Technische Universität Dresden, Dresden
- URN Qucosa
- urn:nbn:de:swb:14-1169028775210-26417
- Veröffentlichungsdatum Qucosa
- 17.01.2007
- Dokumenttyp
- Dissertation
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis
