- AutorIn
- Akram Youssef Technische Universität Dresden, Klinikum Chemnitz
- Christian PflueckeTechnische Universität Dresden, Universitätsklinikum Carl Gustav Carus, Herzzentrum Dresden
- Maciej DawidTechnische Universität Dresden, Klinikum Chemnitz
- Karim Ibrahim
- Michael Günther
- Steffen Kolschmann
- Utz Richter
- Alexander Francke
- Carsten Wunderlich
- Marian Christoph
- Titel
- The short term influence of right ventricular pacing burden on echocardiographic and spiroergometric parameters in patients with preserved left ventricular ejection fraction
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:14-qucosa2-895067
- Quellenangabe
- BMC cardiovascular disorders
Erscheinungsjahr: 2022
Jahrgang: 22
E-ISSN: 1471-2261
Artikelnummer: 23 - Erstveröffentlichung
- 2022
- Abstract (EN)
- Background The incidence of worsened clinical outcome due to high right ventricular (RV) pacing burden in patients with preserved left ventricular function remains controversial. Objective To investigate the impact of RV pacing on several echocardiographic and spiroergometric parameters. Methods In 60 pacemaker patients with preserved left ventricular ejection fraction (LVEF) serial echocardiographies and spiroergometries were performed over a time course of 12 months. Additionally, in 48 patients retrospective echocardiographic analyses of the LV- and RV function were carried out up to 24 months after pacemaker implantation. Results The patients were divided into two groups: The high RV pacing burden group (hRVP: ≥ 40%) and the low RV pacing group (lRVP < 40%) according to the definitions in previous randomized MOST and DAVID trials. After a period of 12-month pacemaker therapy no changes to left ventricular end diastolic diameter (LVEDD), left ventricular end systolic diameter (LVESD), LVEF, E/A-ratio; E/E′-ratio and tricuspid annular plane systolic excursion (TAPSE) could be revealed, independently of the RV pacing burden. Additionally, after 24-month long term follow-up there were no differences in LVEF and TAPSE in both groups. Accordingly, no relevant changes of peak exercise capacity, ventilatory anaerobic threshold or maximal oxygen consumption could be demonstrated independently of the RV pacing. Conclusions In pacemaker patients with preserved LVEF the burden of RV pacing has no adverse influence on several echocardiographic and spiroergometric surrogate parameters of pacemaker-induced cardiomyopathy after a follow-up of 12 to 24 month. Despite this, screening for pacemaker induced cardiomyopathy should be performed especially in the presence of new heart failure symptoms.
- Andere Ausgabe
- Link zum Artikel der zuerst in der Zeitschrift „BMC Cardiovascular Disorders” bei BioMed Central erschienen ist.
DOI: 10.1186/s12872-021-02429-0 - Freie Schlagwörter (DE)
- Ventrikuläre Stimulation, Herzschrittmacher, Echokardiographie, Spiroergometrie, Klinisches Ergebnis
- Freie Schlagwörter (EN)
- Ventricular pacing, Pacemaker, Echocardiography, Spiroergometry, Clinical outcome
- Klassifikation (DDC)
- 610
- Verlag
- BioMed Central, London
- Version / Begutachtungsstatus
- publizierte Version / Verlagsversion
- URN Qucosa
- urn:nbn:de:bsz:14-qucosa2-895067
- Veröffentlichungsdatum Qucosa
- 22.04.2024
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis
CC BY 4.0