- Titel
- Evaluation of Magnetic Resonance Imaging/ Ultrasound-Fusion Biopsy in Patients with Low-Risk Prostate Cancer Under Active Surveillance Undergoing Surveillance Biopsy
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:14-qucosa2-706401
- Quellenangabe
- Urologia Internationalis Erscheinungsort: Basel
Verlag: Karger
Erscheinungsjahr: 2018
Jahrgang: 100
Heft: 2
Seiten: 155-163
ISSN: 0042-1138
E-ISSN: 1423-0399 - Erstveröffentlichung
- 2018
- Abstract (EN)
- Introduction: Targeted biopsy of tumour-suspicious lesions detected in multiparametric magnetic resonance imaging (mpMRI) plays an increasing role in the active surveillance (AS) of patients with low-risk prostate cancer (PCa). The aim of this study was to compare MRI/ultrasound-fusion biopsy (fusPbx) with systematic biopsy (sysPbx) in patients undergoing biopsy for AS. Methods: Patients undergoing mpMRI and transperineal fusPbx combined with transrectal sysPbx (comPbx) as surveillance biopsy were investigated. The detection of Gleason score upgrading and reclassification according to Prostate Cancer Research International Active Surveillance criteria were evaluated. Results: Eighty-three patients were enrolled. PCa upgrading was detected in 39% by fusPbx and in 37% by sysPbx (p = 1.0). The percentage of patients who were reclassified in fusPbx and sysPbx (p = 0.45) were 64 and 59% respectively. ComPbx detected more frequently tumour upgrading than fusPbx (71 vs. 64%, p = 0.016) and sysPbx (71 vs. 59%, p < 0.001) and more patients had to be reclassified after comPbx than after fusPbx or sysPbx alone. Conclusions: The combination of fusPbx and sysPbx outperforms both modalities alone with regard to the detection of upgrading and reclassification in patients under AS. Because a high missing rate of significant PCa still exists in both biopsy modalities, a combination of fusPbx and sysPbx should be recommended in these patients.
- Andere Ausgabe
- Link zum Artikel der zuerst in der Zeitschrift 'Urologia Internationalis' erschienen ist
DOI: 10.1159/000486041 - Freie Schlagwörter (DE)
- Magnetresonanztomographie/Ultraschall-Fusionsbiopsie, Prostatakrebs mit geringem Risiko, Multiparametrische Magnetresonanztomographie, Systematische Biopsie, Aktive Überwachung
- Freie Schlagwörter (EN)
- Magnetic resonance imaging/ultrasound-fusion biopsy, Low-risk prostate cancer, Multiparametric magnetic resonance imaging, Systematic biopsy, Active surveillance
- Klassifikation (DDC)
- 610
- Verlag
- Karger, Basel
- Version / Begutachtungsstatus
- publizierte Version / Verlagsversion
- URN Qucosa
- urn:nbn:de:bsz:14-qucosa2-706401
- Veröffentlichungsdatum Qucosa
- 26.05.2020
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis
